DNA exploration, with the evidence in view

Your DNA file.
A richer view of
what’s inside.

GenomeVia connects your 23andMe data with scientific reference sources and brings the results together in an explorable report—so you can understand what matched, why it matters for research, and where the evidence comes from.

A DNA analysis service in development for curious DNA owners and citizen scientists. The current focus is raw 23andMe data, not a new DNA test.

GenomeVia / Your resultsEvidence at every step
One connected report

Explore the result.
Follow the evidence.

Your DNA dataReference sourcesGenomeVia analysis
01
What’s in your file?

Marker records, DNA-letter pairs, and usable data.

02
What did each source add?

Clinical submissions, predicted effects, and population context.

03
How was this result connected?

Matching rules, contributing records, and source details.

04
Where can I go deeper?

Browse conditions, variants, and supporting research.

Illustrative report structure, not a screenshot or personal result.

Start with DNA data you already have

Explore more context around your raw 23andMe file.

Bring several evidence layers together

See different scientific questions in one report.

Understand the connection

Keep results linked to your data and their sources.

From upload to understanding

More context. A clear path through it.

You bring your raw DNA file. GenomeVia organizes its records, connects them to reference evidence, and gives you a report you can explore at your own pace.

  1. 01 / UPLOAD

    Bring your 23andMe file

    Start with raw 23andMe marker data. The current supported format uses GRCh37, the reference map named in the file header.

  2. 02 / PREPARE

    Understand your starting data

    See which marker records and reported DNA-letter pairs can be used, and which cannot.

  3. 03 / AUGMENT

    Add scientific context

    Connect matching records with clinical submissions, molecular predictions, population frequencies, and medication-related research.

  4. 04 / EXPLORE

    Follow the results

    Start with summaries, then browse detailed records and the sources that support them.

The report experience

Useful questions. Evidence you can inspect.

Explore four core report areas, from your starting data to the reference evidence around it. GenomeVia is refining this experience ahead of public access.

Your data & coverage

What was actually found in my file?

Understand your uploaded records before interpreting added evidence. See usable calls, source-matching coverage, and where information is missing.

A missing source match is a coverage result. It does not establish that a DNA difference has no biological relevance.

The report helps you follow
  • Uploaded marker records and their reported DNA letters.
  • Matched, unmatched, and unusable records.
  • The difference between no source record and a processing failure.
  • The source information added to your data.
Clinical submissions

Has this DNA difference been reported?

The ClinVar Explorer groups applicable submitted classifications by condition or response, with links back to the marker and DNA-letter pair in your file.

A condition label is a way to browse source records. It is not a diagnosis; submitted interpretations may be uncertain or conflicting.

The report helps you follow
  • Condition-first browsing into detailed source records.
  • Submitted classifications and review strength.
  • Matching context and your reported genotype.
  • The evidence behind a classification.
Effects & frequency

What might it affect, and how common is it?

Explore molecular-effect predictions from Ensembl VEP alongside allele-frequency data from gnomAD. GenomeVia’s combined analysis explains which records meet its research filters and adds applicable ClinVar context.

Rare does not mean harmful. A predicted molecular effect is not a measure of personal health risk.

The report helps you follow
  • Predicted gene, transcript, and protein consequences.
  • Frequency groups in reference populations.
  • Same-allele connections between sources.
  • Every count and selection rule in the combined analysis.
Medication context

Do combinations of my markers add context?

Pharmacogenomics studies genetic factors related to medication response. GenomeVia uses defined marker combinations to produce gene-level research results while preserving the markers that contributed.

Missing markers can limit a result. This context is not prescribing guidance and does not tell you to change medication.

The report helps you follow
  • Gene-level results from defined rules.
  • The marker combinations that contributed.
  • Confidence and missing-marker information.
  • How the result relates to medication-response research.
The science behind the context

Different sources answer different questions.

A marker ID (rsID) names a recorded DNA location. An allele is one DNA version there; your genotype is the version or pair reported in your file. GenomeVia uses these connections to bring the right evidence into view.

Source or analysisThe questionWhat it contributes
dbSNPWhich recorded DNA difference is this?

Variant identity, genome position, and allele context for matching.

ClinVarWhat interpretations have been submitted?

Clinical classifications, condition or response labels, and review strength.

Ensembl VEPWhat might this difference affect?

Predicted consequences for genes, transcripts, and proteins.

gnomADHow common is this allele in reference populations?

Population-frequency context for matching alleles.

GenomeVia PGx analysisDo marker combinations have medication-related context?

Rule-based gene-level results, contributing markers, and coverage limits.

Source coverage varies with your file, available reference data, and the matching method. GenomeVia explains those limits alongside the results.

Why choose GenomeVia?

A richer report should also be easier to understand.

Adding reference information is the beginning. GenomeVia is being built to help you follow the reasoning, see the full context, and keep exploring without losing your place.

01 / CONNECTION

Keep your DNA connected to the evidence

Follow a result back to your marker and reported DNA letters. See what came from a source and what GenomeVia calculated or combined.

02 / CONTEXT

See the whole picture before the details

Start with source-wide summaries and matching counts. Combined analyses show the rules that narrowed the results, with detailed browsing and supplemental exports.

03 / UNDERSTANDING

Explore at the depth that suits you

Begin with a plain-language question, move into a topic or condition, and inspect source records when you want more detail. Uncertainty and missing evidence stay visible.

Where GenomeVia is progressing

A broader view of the research around your DNA.

Implemented · grouping under review

Browse research by topic

Explore GWAS Catalog associations through topics, publications, and marker IDs. Genome-wide association studies connect DNA locations with measured traits; personal effects are not yet assessed in these topic summaries.

Implemented · report experience evolving

Explore tissue and gene activity

GTEx and regulatory evidence add research context about gene activity in tissues. Protein and gene-level reference layers offer further routes into biological detail.

Model scoring · interpretation limited

Understand polygenic models

Polygenic models combine information from many DNA locations. GenomeVia can calculate model-specific scores and report coverage; population percentiles and calibrated personal-risk estimates are not available.

Explore responsibly

Research context, with its limits explained.

GenomeVia is being developed as an educational DNA research service. Your raw 23andMe file covers selected markers rather than your complete genome.

  • Submitted interpretations and molecular predictions do not establish a diagnosis.
  • Population frequency and model scores do not automatically describe your personal health risk.
  • Medical or medication decisions require appropriate clinical confirmation and professional guidance.

Common questions

Do I need another DNA test?

The current workflow starts with the raw data file from a 23andMe test you have already taken. GenomeVia augments that data with reference information.

Does GenomeVia support other DNA providers?

The current MVP focuses on 23andMe rsID data using GRCh37. Additional providers, formats, and reference builds are future work.

Will every marker have a result?

No. Sources cover different questions and different DNA differences. The report shows what matched, what did not, and why coverage is limited.

Can I upload my file from this page?

For questions about access or interest in an early beta, reach out at contact@genomevia.com.

More context. Connected evidence. Room to explore.

Explore more of what your 23andMe data can tell you.

GenomeVia brings clinical submissions, predicted molecular effects, population frequencies, and medication-related research together in one explorable report. Follow the connections back to your DNA data and the scientific sources behind each result.

Have a question or interested in joining an early beta? Reach out at contact@genomevia.com.